Mismatch Negativity and Complex Second-Order Sensory Memory in Schizophrenia
Principal Investigator: DF Salisbury
Project period: 5/1/2012 – 4/30/2017
Purpose: To investigate complex acoustic pattern analysis and echoic memory abnormalities in schizophrenia utilizing electrophysiological measures, and compare and contrast these dysfunctions with control subjects to provide novel measures of brain dysfunction.
Cortical Cells, Circuits, Connectivity and Cognition in Schizophrenia
Principal Investigator: DA Lewis
Project Period: 4/1/2014 – 3/31/2019
Project 5 Co-Principal Investigators: B Luna & DF Salisbury
Project 5 Title: Alterations of Cortical Connectivity and Cognition in Schizophrenia
Purpose: To determine how basic cellular and circuit abnormalities identified in post-mortem and animal model work (Projects 1 – 4) give rise to cortical network and cognitive disturbances in medication naïve, first-episode psychosis.